Familiar published CTA families and studied targets
The named panel has 113 protein records. The complete curated published-target list has 2233 records and is available in the searchable report. Current categories use the fivefold rule.
| Protein | Current classification | Highest normal TPM | Context | Recorded reason | Published nominations |
|---|---|---|---|---|---|
| ACRBP | Unsafe | 37.5 | blood / non-classical monocyte | Normal bulk ; HPA tissue clusters ; HPA immune ; Monaco immune ; DICE immune | Chang et al. (2019); Wang et al. (2016) |
| AKAP4 | CTA | 0.079 | blood / natural killer cells | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Wang et al. (2016); da Silva et al. (2017) |
| CAGE1 | CTA | 1.056 | blood / stimulated CD4 T cells | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Wang et al. (2016); da Silva et al. (2017) |
| CEP55 | Unsafe | 35.2 | thymus | HPA normal protein ; Normal bulk ; HPA tissue clusters ; DICE immune ; Adult cornea ; Rare vital-tissue cell expression | — |
| CSAG1 | Unsafe | 1.352 | Brain Caudate basal ganglia | Rare vital-tissue cell expression | Wang et al. (2016) |
| CSAG2 | CTA | 1.3 | lymph node | Cancer and reproductive/developmental evidence qualify | Jamin et al. (2021) |
| CSAG3 | CTA | 2.2 | spleen | Cancer and reproductive/developmental evidence qualify | Jamin et al. (2021) |
| CT45A1 | CTA | 0.9 | retina | Cancer and reproductive/developmental evidence qualify | Jamin et al. (2021); Loriot et al. (2025); da Silva et al. (2017) |
| CT45A10 | CTA | 2.3 | reticular pontine nucleus, oral | Cancer and reproductive/developmental evidence qualify | Loriot et al. (2025) |
| CT45A2/8/9 | CTA | 0.2 | parahippocampal cortex (white matter) | Cancer and reproductive/developmental evidence qualify | Jamin et al. (2021); Loriot et al. (2025); da Silva et al. (2017) |
| CT45A3 | Other:Sequence | 1.1 | hypothalamus | Nested or Unsafe-contained sequence | Jamin et al. (2021); Loriot et al. (2025); da Silva et al. (2017) |
| CT45A5/6/7 | Unsafe | 7.6 | putamen | Normal bulk | Jamin et al. (2021); Loriot et al. (2025); da Silva et al. (2017) |
| CT47A1/10/11/12/2/3/4/5/6/7/8/9 | CTA | 0.9 | blood / Memory CD4 T-cell Th2 | Cancer and reproductive/developmental evidence qualify | Loriot et al. (2025); Wang et al. (2016) |
| CT83 | CTA | 1.7 | salivary gland | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| CTAG2 | CTA | 3.9 | thymus | Cancer and reproductive/developmental evidence qualify | Loriot et al. (2025); Seager et al. (2024); da Silva et al. (2017) |
| CTAGE1 | CTA | 0.217 | blood / naive B cells | Cancer and reproductive/developmental evidence qualify | da Silva et al. (2017) |
| CTCFL | Unsafe | 11.8 | parieto-temporal junction (white matter) | Normal bulk | Bruggeman et al. (2018); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| DDX43 | Unsafe | 21.093 | blood / natural killer cells | HPA normal protein ; HPA tissue clusters ; Monaco immune ; DICE immune ; Rare vital-tissue cell expression | Bruggeman et al. (2018); Chang et al. (2019); Wang et al. (2016) |
| DPEP3 | Unsafe | 22.1 | blood / neutrophil | Normal bulk ; Monaco immune | Bruggeman et al. (2018); Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| FATE1 | Unsafe | 3 | thymus | HPA tissue clusters ; Rare vital-tissue cell expression | Bruggeman et al. (2018); Chang et al. (2019); Wang et al. (2016); da Silva et al. (2017) |
| GAGE1 | CTA | 0.7 | retina | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Seager et al. (2024); Wang et al. (2016); da Silva et al. (2017) |
| GAGE10 | CTA | 3.619 | blood / memory regulatory T cells | Cancer and reproductive/developmental evidence qualify | Seager et al. (2024) |
| GAGE12B | Unsafe | 13 | blood / naive CD4 T-cell | Monaco immune | Jamin et al. (2021) |
| GAGE12C/D/E | CTA | 0.3 | area striata | Cancer and reproductive/developmental evidence qualify | Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| GAGE12F/G | Unsafe | 17 | stomach | HPA immune | Jamin et al. (2021); Loriot et al. (2025) |
| GAGE12H | CTA | 0 | No supported positive measurement | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025) |
| GAGE12J | CTA | 3.1 | retina | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Seager et al. (2024); Wang et al. (2016); da Silva et al. (2017) |
| GAGE13 | CTA | 2 | retina | Cancer and reproductive/developmental evidence qualify | Loriot et al. (2025); Seager et al. (2024); da Silva et al. (2017) |
| GAGE2A | CTA | 1.1 | retina | Cancer and reproductive/developmental evidence qualify | Carter et al. (2023); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| GAGE2E | Other:Review | 17.8 | stomach | Identity or translation requires review ; Nested or Unsafe-contained sequence | Jamin et al. (2021); Loriot et al. (2025); da Silva et al. (2017) |
| HORMAD1 | Unsafe | 17.984 | blood / monocytes | HPA tissue clusters ; DICE immune ; Adult cornea | Bruggeman et al. (2018); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| HSPB9 | Unsafe | 5.21 | Liver | Normal bulk ; HPA tissue clusters | — |
| IGF2BP3 | Unsafe | 6.5 | tonsil | HPA normal protein ; HPA tissue clusters ; Rare vital-tissue cell expression | Bradley et al. (2020); Bruggeman et al. (2018); Chang et al. (2019); Jamin et al. (2021); Wang et al. (2016) |
| LDHC | Unsafe | 4.618 | blood / naive CD4 T cells | Normal bulk ; HPA tissue clusters ; Adult cornea ; Rare vital-tissue cell expression | Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| LIPI | Unsafe | 4.1 | thyroid gland | HPA tissue clusters ; Rare vital-tissue cell expression | — |
| LY6K | Unsafe | 10.884 | Esophagus Mucosa | Normal bulk ; HPA tissue clusters ; Adult cornea ; Rare vital-tissue cell expression | Chang et al. (2019); Wang et al. (2016) |
| MAGEA1 | CTA | 0 | No supported positive measurement | Cancer and reproductive/developmental evidence qualify | Carter et al. (2023); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Seager et al. (2024); Wang et al. (2016); da Silva et al. (2017) |
| MAGEA10 | CTA | 2.2 | angular gyrus (white matter) | Cancer and reproductive/developmental evidence qualify | Carter et al. (2023); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Seager et al. (2024); Wang et al. (2016) |
| MAGEA11 | CTA | 0.147 | Esophagus Mucosa | Cancer and reproductive/developmental evidence qualify | Carter et al. (2023); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| MAGEA12 | Unsafe | 0.328 | Brain Caudate basal ganglia | Rare vital-tissue cell expression | Carter et al. (2023); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Seager et al. (2024); Wang et al. (2016); da Silva et al. (2017) |
| MAGEA2/B | CTA | 0.6 | parieto-temporal junction (white matter) | Cancer and reproductive/developmental evidence qualify | Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| MAGEA3 | Unsafe | 0.2 | adipose tissue | HPA tissue clusters | Bruggeman et al. (2018); Carter et al. (2023); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Seager et al. (2024); Wang et al. (2016); da Silva et al. (2017) |
| MAGEA4 | CTA | 0.7 | lymph node | Cancer and reproductive/developmental evidence qualify | Bruggeman et al. (2018); Carter et al. (2023); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Seager et al. (2024); Wang et al. (2016); da Silva et al. (2017) |
| MAGEA6 | CTA | 0.2 | adipose tissue | Cancer and reproductive/developmental evidence qualify | Carter et al. (2023); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| MAGEA8 | CTA | 0.989 | blood / naive B cells | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| MAGEA9/B | CTA | 0.2 | adipose tissue | Cancer and reproductive/developmental evidence qualify | Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| MAGEB1 | CTA | 0 | No supported positive measurement | Cancer and reproductive/developmental evidence qualify | Bruggeman et al. (2018); Carter et al. (2023); Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| MAGEB10 | CTA | 1.9 | parieto-temporal junction (white matter) | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Wang et al. (2016) |
| MAGEB16 | CTA | 0 | No supported positive measurement | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| MAGEB17 | CTA | 1.851 | Esophagus Gastroesophageal Junction | Cancer and reproductive/developmental evidence qualify | — |
| MAGEB18 | CTA | 0 | No supported positive measurement | Cancer and reproductive/developmental evidence qualify | Wang et al. (2016); da Silva et al. (2017) |
| MAGEB2 | Unsafe | 0.3 | blood / Exhausted memory B-cell | HPA tissue clusters | Bruggeman et al. (2018); Carter et al. (2023); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| MAGEB3 | CTA | 0.2 | corpus callosum, genu (white matter) | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Wang et al. (2016); da Silva et al. (2017) |
| MAGEB4 | CTA | 0 | No supported positive measurement | Cancer and reproductive/developmental evidence qualify | da Silva et al. (2017) |
| MAGEB5 | Reproductive Antigen only | 0.039 | Minor Salivary Gland | Reproductive/developmental evidence qualifies; Patient identity is unresolved for potentially qualifying repeated tumor samples | — |
| MAGEB6 | Unsafe | 0 | No supported positive measurement | HPA normal protein | Carter et al. (2023); Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| MAGEB6B | Cancer Antigen only | 0 | No supported positive measurement | Cancer evidence qualifies; no qualifying reproductive/developmental association recorded | — |
| MAGEC1 | CTA | 0.5 | parieto-temporal junction (white matter) | Cancer and reproductive/developmental evidence qualify | Carter et al. (2023); Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| MAGEC2 | Other:Review | 0.1 | corticomedial amygdala | Normal-expression evidence blocks admission | Carter et al. (2023); Chang et al. (2019); Loriot et al. (2025); Seager et al. (2024); Wang et al. (2016); da Silva et al. (2017) |
| MAGEC3 | Unsafe | 8.9 | parieto-temporal junction (white matter) | Normal bulk ; HPA tissue clusters ; Rare vital-tissue cell expression | — |
| NY-ESO-1 | CTA | 0.3 | flocculonodular lobe | Cancer and reproductive/developmental evidence qualify | Jamin et al. (2021); Loriot et al. (2025); Seager et al. (2024); Wang et al. (2016); da Silva et al. (2017) |
| OIP5 | Unsafe | 11.7 | thymus | Normal bulk ; HPA tissue clusters ; Monaco immune ; Rare vital-tissue cell expression | Chang et al. (2019); Wang et al. (2016) |
| PAGE1 | CTA | 0 | No supported positive measurement | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| PAGE2 | CTA | 1.6 | blood / Memory CD4 T-cell Th17 | Cancer and reproductive/developmental evidence qualify | Carter et al. (2023); Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| PAGE2B | Unsafe | 5.172 | blood / naive B cells | HPA tissue clusters | Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| PAGE3 | CTA | 0.3 | nucleus tractus solitarii | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019) |
| PAGE4 | Unsafe | 35.1 | smooth muscle | Normal bulk | — |
| PAGE5 | Unsafe | 5.518 | blood / THSTAR | HPA tissue clusters | Carter et al. (2023); Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| PBK | Unsafe | 29.4 | thymus | Normal bulk ; HPA tissue clusters ; Adult cornea ; Rare vital-tissue cell expression | Chang et al. (2019); Wang et al. (2016); da Silva et al. (2017) |
| PIWIL1 | Unsafe | 1.6 | retina | HPA tissue clusters | Chang et al. (2019); Jamin et al. (2021); Wang et al. (2016); da Silva et al. (2017) |
| PIWIL2 | Unsafe | 5.9 | duodenum | Normal bulk ; HPA tissue clusters ; Adult cornea ; Rare vital-tissue cell expression | Bruggeman et al. (2018); Chang et al. (2019); Wang et al. (2016) |
| PIWIL4 | Unsafe | 17.487 | blood / M2 | HPA normal protein ; Normal bulk ; HPA tissue clusters ; DICE immune ; Rare vital-tissue cell expression | — |
| PLAC1 | Unsafe | 0.491 | blood / natural killer cells | Rare vital-tissue cell expression | Bradley et al. (2020); Wang et al. (2016) |
| PRAME | CTA | 3 | adrenal gland | Cancer and reproductive/developmental evidence qualify | Bruggeman et al. (2018); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| ROPN1 | Unsafe | 2.7 | salivary gland | HPA tissue clusters | Bruggeman et al. (2018); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| ROPN1B | Unsafe | 6.7 | skin | Normal bulk ; HPA tissue clusters ; Adult cornea | Bruggeman et al. (2018); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| ROPN1L | Unsafe | 36.6 | blood / neutrophil | HPA normal protein ; Normal bulk ; HPA tissue clusters ; HPA immune ; Monaco immune ; DICE immune ; Rare vital-tissue cell expression | Chang et al. (2019); Jamin et al. (2021); Wang et al. (2016) |
| SAGE1 | CTA | 0.919 | blood / THSTAR | Cancer and reproductive/developmental evidence qualify | Carter et al. (2023); Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| SPA17 | Unsafe | 14.7 | pituitary gland | HPA normal protein ; Normal bulk ; HPA tissue clusters ; Adult cornea ; Rare vital-tissue cell expression | Chang et al. (2019); Wang et al. (2016); da Silva et al. (2017) |
| SPACA1 | CTA | 0.2 | ventromedial nucleus | Cancer and reproductive/developmental evidence qualify | Carter et al. (2023); Chang et al. (2019); Wang et al. (2016); da Silva et al. (2017) |
| SPAG1 | Unsafe | 22.533 | blood / stimulated CD4 T cells | HPA normal protein ; Normal bulk ; HPA tissue clusters ; DICE immune ; Adult cornea ; Rare vital-tissue cell expression | Jamin et al. (2021) |
| SPAG9 | Unsafe | 202.027 | blood / stimulated CD4 T cells | HPA normal protein ; Normal bulk ; HPA tissue clusters ; HPA immune ; Monaco immune ; DICE immune ; Adult cornea ; Rare vital-tissue cell expression | Garg et al. (2007) |
| SPANXA1/2 | CTA | 3 | retrosplenial cortex | Cancer and reproductive/developmental evidence qualify | Jamin et al. (2021); Wang et al. (2016); da Silva et al. (2017) |
| SPANXB1 | CTA | 2.1 | parahippocampal cortex (white matter) | Cancer and reproductive/developmental evidence qualify | Jamin et al. (2021); Loriot et al. (2025) |
| SPANXC | CTA | 2.7 | paraventricular nucleus | Cancer and reproductive/developmental evidence qualify | Carter et al. (2023); Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| SPANXD | CTA | 2.6 | preoptic area | Cancer and reproductive/developmental evidence qualify | Carter et al. (2023); Chang et al. (2019); Loriot et al. (2025) |
| SPANXN1 | CTA | 0.236 | blood / TH17 | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019) |
| SPANXN2 | CTA | 0 | No supported positive measurement | Cancer and reproductive/developmental evidence qualify | — |
| SPANXN3 | CTA | 0.8 | duodenum | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Wang et al. (2016) |
| SPANXN4 | CTA | 0.5 | hippocampus, CA3 | Cancer and reproductive/developmental evidence qualify | — |
| SPANXN5 | CTA | 0 | No supported positive measurement | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Wang et al. (2016) |
| SSX1 | CTA | 1.2 | cerebellar cortex | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| SSX2/B | CTA | 2.4 | lateral hypothalamic area | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Jamin et al. (2021); Loriot et al. (2025); Seager et al. (2024); Wang et al. (2016); da Silva et al. (2017) |
| SSX3 | CTA | 1.5 | ventromedial nucleus | Cancer and reproductive/developmental evidence qualify | Carter et al. (2023); Chang et al. (2019); Jamin et al. (2021); Wang et al. (2016); da Silva et al. (2017) |
| SSX4/B | CTA | 0.2 | paracentral lobule, posterior | Cancer and reproductive/developmental evidence qualify | Jamin et al. (2021); da Silva et al. (2017) |
| SSX5 | CTA | 3.5 | ventromedial nucleus | Cancer and reproductive/developmental evidence qualify | Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| SSX7 | Unsafe | 6 | temporal white matter | Normal bulk | Wang et al. (2016) |
| SYCP1 | CTA | 1.938 | blood / naive B cells | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| SYCP2 | Unsafe | 39.504 | blood / natural killer cells | Normal bulk ; HPA tissue clusters ; Monaco immune ; DICE immune ; Rare vital-tissue cell expression | Chang et al. (2019); Jamin et al. (2021); Wang et al. (2016) |
| SYCP3 | Unsafe | 8.282 | blood / natural killer cells | HPA tissue clusters ; DICE immune ; Rare vital-tissue cell expression | Bruggeman et al. (2018); Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| TEX101 | Unsafe | 74.9 | blood / basophil | Normal bulk ; HPA tissue clusters ; HPA immune ; Monaco immune | Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016); da Silva et al. (2017) |
| TPTE | Unsafe | 2 | parieto-temporal junction (white matter) | Rare vital-tissue cell expression | Bruggeman et al. (2018); Jamin et al. (2021); da Silva et al. (2017) |
| TSGA10 | Unsafe | 15.12 | blood / naive CD8 T cells | Normal bulk ; HPA tissue clusters ; DICE immune ; Adult cornea ; Rare vital-tissue cell expression | Chang et al. (2019); Wang et al. (2016) |
| TSPY1 | CTA | 0 | No supported positive measurement | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016) |
| TSPY10/3 | CTA | 0.2 | esophagus | Cancer and reproductive/developmental evidence qualify | Loriot et al. (2025); Wang et al. (2016) |
| TSPY2 | CTA | 0.4 | somatosensory cortex, postcentral gyrus, ventral (white matter) | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016) |
| TSPY4 | CTA | 0.2 | spleen | Cancer and reproductive/developmental evidence qualify | Loriot et al. (2025); Wang et al. (2016) |
| TSPY8 | CTA | 0 | No supported positive measurement | Cancer and reproductive/developmental evidence qualify | — |
| TSPY9 | CTA | 0.2 | spleen | Cancer and reproductive/developmental evidence qualify | Loriot et al. (2025) |
| XAGE1A/B | CTA | 1.8 | lung | Cancer and reproductive/developmental evidence qualify | Loriot et al. (2025); Seager et al. (2024) |
| XAGE2 | Unsafe | 8.1 | lung | Normal bulk ; HPA tissue clusters ; Rare vital-tissue cell expression | — |
| XAGE3 | CTA | 3.1 | adipose tissue | Cancer and reproductive/developmental evidence qualify | Wang et al. (2016) |
| XAGE5 | CTA | 1.641 | blood / follicular helper T cells | Cancer and reproductive/developmental evidence qualify | Chang et al. (2019); Loriot et al. (2025); Wang et al. (2016) |