{
  "historical_policy_id": "oncoref.target-sets.2026-10-25.2",
  "historical_assets": {
    "release": "https://github.com/pirl-unc/oncoref/releases/tag/v1.20.0",
    "download_base": "https://github.com/pirl-unc/oncoref/releases/download/v1.20.0/",
    "sha256": {
      "additional-forbidden.fasta.gz": "78afcc20aa70ece5f29cee021d2ba91d30552e3e1144a348c6ac56fc7254e560",
      "cta-proteins.csv.gz": "e8f1e1cc37b91a8ee431c32533a8c2c0282eb8c5c41bd2964cb67184f884a763",
      "cta.fasta.gz": "fc209c396ab705d0db0eb9a3b02e92eaebf154c1fd78c90fa05e73440c1fc9bc",
      "exclusion-basis.json": "7cb9fcc59d377943bff2322914e66cc0d63494442301a12123adf3fd8fdacdfc",
      "genes-without-complete-proteins.csv.gz": "3a69eaed2467e9535c75b5eae584ea54bb6ded000ae96bc9bc73d8c034359951",
      "neither-proteins.csv.gz": "dfab08b40584ba896aeb0b56082594e7f71bdac894f9c7c2673b15614473db1f",
      "neither.fasta.gz": "575cc62b9d77fe873879ad85a45ce77cf86d212a7ce2e73465b87a0c2542e336",
      "reference.json": "2704cc979a2bac44d92557fe574388a9a977b8be604e1f554120411f3f7bb3fa",
      "target-protein-occurrences.csv.gz": "26c12a52a6f703a33d6cba79a994da87fe860f25a4dacb46635353b74965f914",
      "target-proteins.csv.gz": "eb1134d10ae08bc1fba0b0b730caf3fdf7d9d6ad98e13d1ae754549a7e8d9cc6",
      "translations-for-review.csv.gz": "1bf3f07dbc50078568fa8cdff0a68da03e3f832795e5f1b369fa91f498b6dcc8",
      "translations-for-review.fasta.gz": "5970c121504d7ce3c2939e5a13c905ffb5ea3901692de2b23c0cd86ce3c2512c",
      "unclassified-sequence-genes.csv.gz": "e1d4263cc49b70e8e5020166232b8a1e19111407abbb196112e50d87e1c7a975",
      "unsafe-proteins.csv.gz": "beb315ca4c348d348df222bb7910fc236f78aebac688819bcafbce98e9aac304",
      "unsafe.fasta.gz": "d93c7c202c0b70d61d53fdc785f2daf4584b062528d2a7a07858fa660a13106f"
    }
  },
  "historical_reference": {
    "schema": "openvax.reference",
    "schema_version": 1,
    "taxon_id": 9606,
    "assembly_accession": "GCA_000001405.29",
    "annotation_source": "Ensembl",
    "annotation_release": "115",
    "source_version": "115",
    "identifier_namespaces": {
      "gene": "Ensembl",
      "protein": "Ensembl",
      "transcript": "Ensembl"
    },
    "content_provenance": {
      "annotation_gtf": "02df5a2a8c7a41e513209e0780c56cf197941b6b35ef8bab3e9a6317eecd17ef",
      "protein_fasta": "7991ab37d09986eefdb5c77032b15370ab0e99918b78f235f3230c0302851c96"
    },
    "reference_id": "openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61"
  },
  "current_bundle_id": "oncoref:sequence-bundle:v1:sha256:c8c060edab62e089fd4651065a857a8eaecb7c68816b016b3ac4c9fd06fa9525",
  "comparison_unit": "SHA-256 of full original amino-acid strings; no partial-segment or approximate equivalence",
  "counts": [
    {
      "historical_forbidden": false,
      "current_role": "allow",
      "sequences": 846
    },
    {
      "historical_forbidden": false,
      "current_role": "exclude",
      "sequences": 1690
    },
    {
      "historical_forbidden": false,
      "current_role": "review",
      "sequences": 2129
    },
    {
      "historical_forbidden": true,
      "current_role": "allow",
      "sequences": 53
    },
    {
      "historical_forbidden": true,
      "current_role": "exclude",
      "sequences": 154113
    },
    {
      "historical_forbidden": true,
      "current_role": "review",
      "sequences": 1980
    }
  ],
  "notes": [
    "Historical Unsafe plus additional-forbidden remains a distinct named product.",
    "Absent sequences require coverage review, never implicit allowance.",
    "Current record roles are combined with exclude > review > allow across all occurrences.",
    "This comparison does not validate an approximate peptide-matching rule."
  ],
  "output_sha256": "1db1dde6a72dc5b69d8a1de0213dc1e67843e576409bdec0c2db33e73a0b8552",
  "generator_sha256": "39ab619adf0c9bfd3008d4b2adefc9105842180da5f67489b61bc0066a680fd5"
}